1LV1

Crystal Structure Analysis of the non-active site mutant of tethered HIV-1 protease to 2.1A resolution

Summary for 1LV1

• Entry DOI: 10.2210/pdb1lv1/pdb
• Related: 1G6L
• Descriptor: HIV-1 protease (2 entities in total)
• Functional Keywords: beta-ribbon flap, hydrolase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P04585
• Total number of polymer chains: 1
• Total formula weight: 21902.76

Authors

Kumar, M.,Kannan, K.K.,Hosur, M.V.,Bhavesh, N.S.,Chatterjee, A.,Mittal, R.,Hosur, R.V. (deposition date: 2002-05-24, release date: 2002-06-19, Last modification date: 2021-11-10)

• Primary citation: Kumar, M.,Kannan, K.K.,Hosur, M.V.,Bhavesh, N.S.,Chatterjee, A.,Mittal, R.,Hosur, R.V.; Effects of remote mutation on the autolysis of HIV-1 PR: X-ray and NMR investigations.; Biochem.Biophys.Res.Commun., 294:395-401, 2002; PubMed: 12051725; DOI: 10.1016/S0006-291X(02)00482-5

Experimental method

X-RAY DIFFRACTION (2.1 Å)