1LTJ

Crystal Structure of Recombinant Human Fibrinogen Fragment D with the Peptide Ligands Gly-Pro-Arg-Pro-Amide and Gly-His-Arg-Pro-Amide

Summary for 1LTJ

Entry DOI	10.2210/pdb1ltj/pdb
Related	1FZA 1FZB 1FZC 1FZE 1FZF 1FZG 1LT9
Descriptor	Fibrinogen alpha/alpha-E chain, Fibrinogen Beta chain, Fibrinogen Gamma chain, ... (8 entities in total)
Functional Keywords	blood coagulation, fibrinogen, fibrinogen fragment d, recombinant fibrinogen fragment d, recombinant fibrinogen, recombinant fibrinogen fragment d with two peptide ligands, blood clotting
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	160899.89
Authors	Kostelansky, M.S.,Betts, L.,Gorkun, O.V.,Lord, S.T. (deposition date: 2002-05-20, release date: 2002-11-06, Last modification date: 2020-07-29)
Primary citation	Kostelansky, M.S.,Betts, L.,Gorkun, O.V.,Lord, S.T. 2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site. Biochemistry, 41:12124-12132, 2002 Cited by PubMed: 12356313 DOI: 10.1021/bi0261894 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation