1LS5

Crystal structure of plasmepsin IV from P. falciparum in complex with pepstatin A

Replaces:  1JGF

Summary for 1LS5

• Entry DOI: 10.2210/pdb1ls5/pdb
• Related: 1SME
• Related PRD ID: PRD_000557
• Descriptor: plasmepsin IV, Pepstatin (3 entities in total)
• Functional Keywords: eukaryotic aspartic proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 4
• Total formula weight: 75342.70

Authors

Asojo, O.A.,Gulnik, S.V.,Afonina, E.,Yu, B.,Ellman, J.A.,Haque, T.S.,Silva, A.M. (deposition date: 2002-05-16, release date: 2002-06-12, Last modification date: 2013-02-27)

• Primary citation: Asojo, O.A.,Gulnik, S.V.,Afonina, E.,Yu, B.,Ellman, J.A.,Haque, T.S.,Silva, A.M.; Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum.; J.Mol.Biol., 327:173-181, 2003; PubMed: 12614616; DOI: 10.1016/S0022-2836(03)00036-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)