1LO0

Catalytic Retro-Diels-Alderase Transition State Analogue Complex

Summary for 1LO0

• Entry DOI: 10.2210/pdb1lo0/pdb
• Related: 1L02 1L03 1L04
• Descriptor: If kappa light chain, Ig gamma 2a heavy chain, 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, ... (4 entities in total)
• Functional Keywords: catalytic antibody, fab fragment, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane; Single-pass membrane protein (Potential): P01865
• Total number of polymer chains: 4
• Total formula weight: 96618.36

Authors

Hugot, M.,Reymond, J.L.,Baumann, U. (deposition date: 2002-05-05, release date: 2002-06-26, Last modification date: 2024-04-03)

• Primary citation: Hugot, M.,Bensel, N.,Vogel, M.,Reymond, M.T.,Stadler, B.,Reymond, J.L.,Baumann, U.; A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.; Proc.Natl.Acad.Sci.USA, 99:9674-9678, 2002; PubMed: 12093912; DOI: 10.1073/pnas.142286599

Experimental method

X-RAY DIFFRACTION (2 Å)