1LL9

Crystal Structure Of AmpC beta-Lactamase From E. Coli In Complex With Amoxicillin

Summary for 1LL9

Entry DOI	10.2210/pdb1ll9/pdb
Related	1FCN 1FR6 1IEL 1IEM 1KE4 1KVM 1LLB
Descriptor	beta-lactamase, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	cephalosporinase, beta-lactamase, serine, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	79543.26
Authors	Trehan, I.,Morandi, F.,Blaszczak, L.C.,Shoichet, B.K. (deposition date: 2002-04-26, release date: 2002-10-02, Last modification date: 2023-08-16)
Primary citation	Trehan, I.,Morandi, F.,Blaszczak, L.C.,Shoichet, B.K. Using steric hindrance to design new inhibitors of class C beta-lactamases. Chem.Biol., 9:971-980, 2002 Cited by PubMed: 12323371 DOI: 10.1016/S1074-5521(02)00211-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation