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1LF2

CRYSTAL STRUCTURE OF PLASMEPSIN II FROM P FALCIPARUM IN COMPLEX WITH INHIBITOR RS370

Summary for 1LF2
Entry DOI10.2210/pdb1lf2/pdb
Related1LF3 1LF4 1LFE
DescriptorPlasmepsin 2, 3-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE (3 entities in total)
Functional Keywordsplasmepsin, plasmodium falciparum, aspartic protease, hydrolase
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Cellular locationVacuole: P46925
Total number of polymer chains1
Total formula weight37611.51
Authors
Asojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Mehadjed, D.,Silva, A.M. (deposition date: 2002-04-10, release date: 2002-10-10, Last modification date: 2021-10-27)
Primary citationAsojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Medjahed, D.,Silva, A.M.
Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370.
Acta Crystallogr.,Sect.D, 58:2001-2008, 2002
Cited by
PubMed: 12454457
DOI: 10.1107/S0907444902014695
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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