1LCY

Crystal Structure of the Mitochondrial Serine Protease HtrA2

Summary for 1LCY

Entry DOI	10.2210/pdb1lcy/pdb
Descriptor	HtrA2 serine protease (2 entities in total)
Functional Keywords	apoptosis, serine protease, pdz domain, caspase activation, iap-binding, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion intermembrane space: O43464
Total number of polymer chains	1
Total formula weight	35001.82
Authors	Li, W.,Srinivasula, S.M.,Chai, J.,Li, P.,Wu, J.W.,Zhang, Z.,Alnemri, E.S.,Shi, Y. (deposition date: 2002-04-07, release date: 2002-05-22, Last modification date: 2024-02-14)
Primary citation	Li, W.,Srinivasula, S.M.,Chai, J.,Li, P.,Wu, J.W.,Zhang, Z.,Alnemri, E.S.,Shi, Y. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Nat.Struct.Biol., 9:436-441, 2002 Cited by PubMed: 11967569 DOI: 10.1038/nsb795 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation