1L6X

FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C

1L6X の概要

• エントリーDOI: 10.2210/pdb1l6x/pdb
• 関連するPDBエントリー: 1DN2
• 分子名称: IMMUNOGLOBULIN GAMMA-1 HEAVY CHAIN CONSTANT REGION, Minimized B-domain of Protein A Z34C, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: igg1 fc, protein a, fc complex, b-domain, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29525.91

構造登録者

Idusogie, E.E.,Presta, L.G.,Santoro-Gazzano, H.,Totpal, K.,Wong, P.Y.,Ultsch, M.,Meng, Y.G.,Mullkerrin, M.G. (登録日: 2002-03-14, 公開日: 2002-04-10, 最終更新日: 2023-08-16)

• 主引用文献: Idusogie, E.E.,Presta, L.G.,Gazzano-Santoro, H.,Totpal, K.,Wong, P.Y.,Ultsch, M.,Meng, Y.G.,Mulkerrin, M.G.; Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc.; J.Immunol., 164:4178-4184, 2000; PubMed: 10754313

実験手法

X-RAY DIFFRACTION (1.65 Å)