1L1R

Crystal Structure of APRTase from Giardia lamblia Complexed with 9-deazaadenine, Mg2+ and PRPP

Summary for 1L1R

• Entry DOI: 10.2210/pdb1l1r/pdb
• Related: 1L1Q
• Descriptor: Adenine phosphoribosyltransferase, MAGNESIUM ION, 9-DEAZAADENINE, ... (5 entities in total)
• Functional Keywords: aprtase, adenine, giardia lamblia, purine metabolism, catalytic loop, transferase
• Biological source: Giardia intestinalis
• Total number of polymer chains: 1
• Total formula weight: 20839.13

Authors

Shi, W.,Sarver, A.E.,Wang, C.C.,Tanaka, K.S.,Almo, S.C.,Schramm, V.L. (deposition date: 2002-02-19, release date: 2002-11-27, Last modification date: 2023-08-16)

• Primary citation: Shi, W.,Sarver, A.E.,Wang, C.C.,Tanaka, K.S.,Almo, S.C.,Schramm, V.L.; Closed Site Complexes of Adenine Phosphoribosyltransferase from Giardia lamblia Reveal a Mechanism of Ribosyl Migration.; J.Biol.Chem., 277:39981-39988, 2002; PubMed: 12171925; DOI: 10.1074/jbc.M205596200

Experimental method

X-RAY DIFFRACTION (1.95 Å)