1KZN

Crystal Structure of E. coli 24kDa Domain in Complex with Clorobiocin

Summary for 1KZN

Entry DOI	10.2210/pdb1kzn/pdb
Descriptor	DNA GYRASE SUBUNIT B, CLOROBIOCIN (3 entities in total)
Functional Keywords	topoisomerase, gyrase b, clorobiocin, isomerase
Biological source	Escherichia coli
Cellular location	Cytoplasm (Potential): P06982
Total number of polymer chains	1
Total formula weight	23288.50
Authors	Lafitte, D.,Lamour, V.,Tsvetkov, P.O.,Makarov, A.A.,Klich, M.,Deprez, P.,Moras, D.,Briand, C.,Gilli, R. (deposition date: 2002-02-07, release date: 2002-06-19, Last modification date: 2024-02-14)
Primary citation	Lafitte, D.,Lamour, V.,Tsvetkov, P.O.,Makarov, A.A.,Klich, M.,Deprez, P.,Moras, D.,Briand, C.,Gilli, R. DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose. Biochemistry, 41:7217-7223, 2002 Cited by PubMed: 12044152 DOI: 10.1021/bi0159837 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation