1KYI

HslUV (H. influenzae)-NLVS Vinyl Sulfone Inhibitor Complex

Summary for 1KYI

Entry DOI	10.2210/pdb1kyi/pdb
Related	1G3I 1G3K 1G41 1JJW
Descriptor	ATP-dependent hsl protease ATP-binding subunit hslU, ATP-dependent protease hslV, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	prokaryotic proteasome, protease, aaa-protein, atp-dependent chaperone; clp/hsp100, vinyl sulfone inhibitor, chaperone-hydrolase complex, chaperone/hydrolase
Biological source	Haemophilus influenzae More
Cellular location	Cytoplasm (By similarity): P43773 P43772
Total number of polymer chains	24
Total formula weight	834898.39
Authors	Sousa, M.C.,Kessler, B.M.,Overkleeft, H.S.,McKay, D.B. (deposition date: 2002-02-04, release date: 2002-05-15, Last modification date: 2023-08-16)
Primary citation	Sousa, M.C.,Kessler, B.M.,Overkleeft, H.S.,McKay, D.B. Crystal Structure of HslUV Complexed with a Vinyl Sulfone Inhibitor: Corroboration of a Proposed Mechanism of Allosteric Activation of HslV by HslU J.Mol.Biol., 318:779-785, 2002 Cited by PubMed: 12054822 DOI: 10.1016/S0022-2836(02)00145-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation