1KIP

FV MUTANT Y(B 32)A (VH DOMAIN) OF MOUSE MONOCLONAL ANTIBODY D1.3 COMPLEXED WITH HEN EGG WHITE LYSOZYME

Summary for 1KIP

• Entry DOI: 10.2210/pdb1kip/pdb
• Related: 1KIQ 1KIR
• Descriptor: MONOCLONAL ANTIBODY D1.3, LYSOZYME, ... (4 entities in total)
• Functional Keywords: immunoglobulin v region, hydrolase, glycosidase, bacteriolytic enzyme, egg white, complex (immunoglobulin-hydrolase), complex (immunoglobulin-hydrolase) complex, complex (immunoglobulin/hydrolase)
• Biological source: Mus musculus (house mouse); More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 3
• Total formula weight: 38797.32

Authors

Fields, B.A.,Poljak, R.J.,Mariuzza, R.A. (deposition date: 1996-10-23, release date: 1996-12-23, Last modification date: 2011-07-13)

• Primary citation: Fields, B.A.,Goldbaum, F.A.,Dall'Acqua, W.,Malchiodi, E.L.,Cauerhff, A.,Schwarz, F.P.,Ysern, X.,Poljak, R.J.,Mariuzza, R.A.; Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozyme.; Biochemistry, 35:15494-15503, 1996; PubMed: 8952503; DOI: 10.1021/bi961709e

Experimental method

X-RAY DIFFRACTION (2.1 Å)