1KE0

X-ray crystal structure of AmpC beta-lactamase from E. coli in complex with the inhibitor 4-(carboxyvin-2-yl)phenylboronic acid

Summary for 1KE0

Entry DOI	10.2210/pdb1ke0/pdb
Related	1C3B 1GA9 1KDS 1KDW 1KE3 1KE4 3BLS
Descriptor	beta-lactamase, PHOSPHATE ION, 4-(CARBOXYVIN-2-YL)PHENYLBORONIC ACID, ... (4 entities in total)
Functional Keywords	cephalosporinase, beta-lactamase, serine hydrolase, phenylboronic acid, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	79654.77
Authors	Powers, R.A.,Shoichet, B.K. (deposition date: 2001-11-13, release date: 2002-07-17, Last modification date: 2023-08-16)
Primary citation	Powers, R.A.,Shoichet, B.K. Structure-based approach for binding site identification on AmpC beta-lactamase. J.Med.Chem., 45:3222-3234, 2002 Cited by PubMed: 12109906 DOI: 10.1021/jm020002p PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation