1KC2

structure of the triple (Lys(beta)D3Ala, Asp(beta)C8Ala, AspCD2Ala) mutant of the Src SH2 domain bound to the PQpYEEIPI peptide

Summary for 1KC2

Entry DOI	10.2210/pdb1kc2/pdb
Descriptor	Src Tyrosine kinase, PQpYEEIPI peptide, COBALT (II) ION, ... (4 entities in total)
Functional Keywords	sh2 domain, phosphotyrosine, transferase
Biological source	Rous sarcoma virus More
Total number of polymer chains	2
Total formula weight	12823.23
Authors	Lubman, O.Y.,Waksman, G. (deposition date: 2001-11-07, release date: 2002-04-17, Last modification date: 2021-11-10)
Primary citation	Lubman, O.Y.,Waksman, G. Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface. J.Mol.Biol., 316:291-304, 2002 Cited by PubMed: 11851339 DOI: 10.1006/jmbi.2001.5362 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation