1KBK

Mechanistic Analyses of Catalysis in Human Pancreatic Alpha-Amylase: Detailed Kinetic and Structural Studies of Mutants of Three Conserved Carboxylic Acids

1KBK の概要

• エントリーDOI: 10.2210/pdb1kbk/pdb
• 分子名称: ALPHA-AMYLASE, PANCREATIC, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: amylase, glycosylation, mutagenesis, diabetes, hydrolase, glycosidase, carbohydrate metabolism, catalysis, pancreatic, enzyme, human
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56184.03

構造登録者

Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G. (登録日: 2001-11-06, 公開日: 2002-04-10, 最終更新日: 2021-10-27)

• 主引用文献: Rydberg, E.H.,Li, C.,Maurus, R.,Overall, C.M.,Brayer, G.D.,Withers, S.G.; Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids.; Biochemistry, 41:4492-4502, 2002; PubMed: 11914097; DOI: 10.1021/bi011821z

実験手法

X-RAY DIFFRACTION (1.9 Å)