1KB4

Crystal Structure of VDR DNA-binding Domain Bound to a Canonical Direct Repeat with Three Base Pair Spacer (DR3) Response Element

Summary for 1KB4

• Entry DOI: 10.2210/pdb1kb4/pdb
• Related: 1KB2 1KB6
• Descriptor: 5'-D(*CP*AP*CP*AP*GP*GP*TP*CP*AP*CP*GP*AP*AP*GP*GP*TP*CP*A)-3', 5'-D(*TP*GP*AP*CP*CP*TP*TP*CP*GP*TP*GP*AP*CP*CP*TP*GP*TP*G)-3', Vitamin D3 Receptor, ... (5 entities in total)
• Functional Keywords: vdr, nuclear receptor, protein-dna complex, vitamin d, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P11473
• Total number of polymer chains: 4
• Total formula weight: 37201.40

Authors

Shaffer, P.L.,Gewirth, D.T. (deposition date: 2001-11-05, release date: 2002-05-03, Last modification date: 2023-08-16)

• Primary citation: Shaffer, P.L.,Gewirth, D.T.; Structural basis of VDR-DNA interactions on direct repeat response elements.; EMBO J., 21:2242-2252, 2002; PubMed: 11980721; DOI: 10.1093/emboj/21.9.2242

Experimental method

X-RAY DIFFRACTION (2.8 Å)