1KAC

KNOB DOMAIN FROM ADENOVIRUS SEROTYPE 12 IN COMPLEX WITH DOMAIN 1 OF ITS CELLULAR RECEPTOR CAR

Summary for 1KAC

Entry DOI	10.2210/pdb1kac/pdb
Related	1NOB
Descriptor	PROTEIN (FIBER KNOB PROTEIN), PROTEIN (COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR) (3 entities in total)
Functional Keywords	adhesion protein receptor complex, viral protein-receptor complex, viral protein/receptor
Biological source	Human adenovirus 12 More
Cellular location	Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Isoform 3: Secreted. Isoform 4: Secreted. Isoform 5: Secreted: P78310
Total number of polymer chains	2
Total formula weight	33584.98
Authors	Bewley, M.C.,Springer, K.,Zhang, Y.B.,Freimuth, P.,Flanagan, J.M. (deposition date: 1999-05-05, release date: 1999-11-24, Last modification date: 2023-12-27)
Primary citation	Bewley, M.C.,Springer, K.,Zhang, Y.B.,Freimuth, P.,Flanagan, J.M. Structural analysis of the mechanism of adenovirus binding to its human cellular receptor, CAR. Science, 286:1579-1583, 1999 Cited by PubMed: 10567268 DOI: 10.1126/science.286.5444.1579 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation