1K8P

Structure of the Human G-quadruplex reveals a novel topology

Summary for 1K8P

• Entry DOI: 10.2210/pdb1k8p/pdb
• Descriptor: 5'-D(*(BRU)P*AP*GP*GP*GP*(BRU)P*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION, SODIUM ION, ... (4 entities in total)
• Functional Keywords: quadruplex dna, double chain reversal loop, dimeric quadruplex, human telomere sequence, g(anti).g(anti).g(anti).g(anti), parallel stranded, dna
• Total number of polymer chains: 2
• Total formula weight: 7907.59

Authors

Parkinson, G.N.,Lee, M.P.H.,Neidle, S. (deposition date: 2001-10-25, release date: 2002-05-31, Last modification date: 2024-02-07)

• Primary citation: Parkinson, G.N.,Lee, M.P.,Neidle, S.; Crystal structure of parallel quadruplexes from human telomeric DNA.; Nature, 417:876-880, 2002; PubMed: 12050675; DOI: 10.1038/nature755

Experimental method

X-RAY DIFFRACTION (2.4 Å)