1K3M
NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
Summary for 1K3M
| Entry DOI | 10.2210/pdb1k3m/pdb |
| Descriptor | INSULIN (2 entities in total) |
| Functional Keywords | hormone, human insulin, mutant, hormone-growth factor complex, hormone/growth factor |
| Cellular location | Secreted: P01308 P01308 |
| Total number of polymer chains | 2 |
| Total formula weight | 5752.51 |
| Authors | Xu, B.,Hua, Q.-X.,Nakagawa, S.H.,Jia, W.,Chu, Y.-C.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2001-10-03, release date: 2001-10-17, Last modification date: 2021-10-27) |
| Primary citation | Xu, B.,Hua, Q.X.,Nakagawa, S.H.,Jia, W.,Chu, Y.C.,Katsoyannis, P.G.,Weiss, M.A. A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci., 11:104-116, 2002 Cited by PubMed: 11742127DOI: 10.1110/ps.ps.32102 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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