1K2P
Crystal structure of Bruton's tyrosine kinase domain
Summary for 1K2P
| Entry DOI | 10.2210/pdb1k2p/pdb |
| Descriptor | Tyrosine-protein kinase BTK (1 entity in total) |
| Functional Keywords | bruton tryosine kinase, kinase domain, transferase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm (By similarity): Q06187 |
| Total number of polymer chains | 2 |
| Total formula weight | 61496.80 |
| Authors | Mao, C.,Zhou, M.,Uckun, F.M. (deposition date: 2001-09-28, release date: 2002-06-26, Last modification date: 2024-02-07) |
| Primary citation | Mao, C.,Zhou, M.,Uckun, F.M. Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia. J.Biol.Chem., 276:41435-41443, 2001 Cited by PubMed: 11527964DOI: 10.1074/jbc.M104828200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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