1K2D

Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A

1K2D の概要

• エントリーDOI: 10.2210/pdb1k2d/pdb
• 分子名称: H-2 class II histocompatibility antigen, A-U alpha chain, H-2 class II histocompatibility antigen, A-U beta chain, Myelin Basic Protein peptide with 8 residue linker peptide, ... (5 entities in total)
• 機能のキーワード: mhc class ii, i-au, h-2u, autoimmune disease, unique register, experimental autoimmune encephalomyelitis, myelin basic protein, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 46946.99

構造登録者

He, X.L.,Radu, C.,Ward, E.S.,Garcia, K.C. (登録日: 2001-09-26, 公開日: 2003-03-04, 最終更新日: 2024-04-03)

• 主引用文献: He, X.L.,Radu, C.,Sidney, J.,Sette, A.,Ward, E.S.,Garcia, K.C.; Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au; IMMUNITY, 17:83-94, 2002; PubMed: 12150894; DOI: 10.1016/S1074-7613(02)00340-0

実験手法

X-RAY DIFFRACTION (2.2 Å)