1K21
HUMAN THROMBIN-INHIBITOR COMPLEX
Summary for 1K21
| Entry DOI | 10.2210/pdb1k21/pdb |
| Related | 1K1I 1K1J 1K1L 1K1M 1K1N 1K1O 1K1P 1K22 |
| Descriptor | Prothrombin, Hirudin variant-2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
| Functional Keywords | serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 36320.25 |
| Authors | Stubbs, M.T.,Musil, D. (deposition date: 2001-09-26, release date: 2002-05-08, Last modification date: 2020-07-29) |
| Primary citation | Dullweber, F.,Stubbs, M.T.,Musil, D.,Sturzebecher, J.,Klebe, G. Factorising ligand affinity: a combined thermodynamic and crystallographic study of trypsin and thrombin inhibition. J.Mol.Biol., 313:593-614, 2001 Cited by PubMed: 11676542DOI: 10.1006/jmbi.2001.5062 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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