1JYU

Xray Structure of Grb2 SH2 Domain

Summary for 1JYU

• Entry DOI: 10.2210/pdb1jyu/pdb
• Related: 1JYQ 1JYR
• Descriptor: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (2 entities in total)
• Functional Keywords: receptor binding, regulatory, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Golgi apparatus (By similarity): P62993
• Total number of polymer chains: 1
• Total formula weight: 11071.56

Authors

Nioche, P.,Liu, W.-Q.,Broutin, I.,Charbonnier, F.,Latreille, M.-T.,Vidal, M.,Roques, B.,Garbay, C.,Ducruix, A. (deposition date: 2001-09-13, release date: 2002-03-13, Last modification date: 2024-02-07)

• Primary citation: Nioche, P.,Liu, W.Q.,Broutin, I.,Charbonnier, F.,Latreille, M.T.,Vidal, M.,Roques, B.,Garbay, C.,Ducruix, A.; Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.; J.Mol.Biol., 315:1167-1177, 2002; PubMed: 11827484; DOI: 10.1006/jmbi.2001.5299

Experimental method

X-RAY DIFFRACTION (2.75 Å)