1JXQ

Structure of cleaved, CARD domain deleted Caspase-9

Summary for 1JXQ

• Entry DOI: 10.2210/pdb1jxq/pdb
• Related: 3YGS
• Descriptor: Caspase-9, benzoxycarbonyl-Val-Ala-Asp-fluoromethyl ketone Inhibitor (3 entities in total)
• Functional Keywords: protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 126794.62

Authors

Renatus, M.,Stennicke, H.R.,Scott, F.L.,Liddington, R.C.,Salvesen, G.S. (deposition date: 2001-09-08, release date: 2001-12-12, Last modification date: 2023-08-16)

• Primary citation: Renatus, M.,Stennicke, H.R.,Scott, F.L.,Liddington, R.C.,Salvesen, G.S.; Dimer formation drives the activation of the cell death protease caspase 9.; Proc.Natl.Acad.Sci.USA, 98:14250-14255, 2001; PubMed: 11734640; DOI: 10.1073/pnas.231465798

Experimental method

X-RAY DIFFRACTION (2.8 Å)