1JU5

Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy

Summary for 1JU5

• Entry DOI: 10.2210/pdb1ju5/pdb
• Related: 1AWO 1AYA 1BBZ 1SPS 2ABL 2PLD
• Descriptor: Crk, Abl (3 entities in total)
• Functional Keywords: crk, sh2, abl, sh3, adaptor protein, phosphopeptide, protein binding-transferase complex, protein binding/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm (By similarity): P46108 Q64010; Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
• Total number of polymer chains: 3
• Total formula weight: 20375.51

Authors

Donaldson, L.W.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D. (deposition date: 2001-08-23, release date: 2002-11-06, Last modification date: 2021-11-10)

• Primary citation: Donaldson, L.W.,Gish, G.,Pawson, T.,Kay, L.E.,Forman-Kay, J.D.; Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide; Proc.Natl.Acad.Sci.USA, 99:14053-14058, 2002; PubMed: 12384576; DOI: 10.1073/pnas.212518799

Experimental method

SOLUTION NMR