1JTZ

CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE.

Summary for 1JTZ

Entry DOI	10.2210/pdb1jtz/pdb
Descriptor	TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11 (2 entities in total)
Functional Keywords	tumor necrosis factor superfamily member, jellyroll, beta-sandwich, cytokine
Biological source	Mus musculus (house mouse)
Cellular location	Isoform 1: Cell membrane; Single-pass type II membrane protein. Isoform 2: Cell membrane; Single-pass type II membrane protein. Isoform 3: Cytoplasm. Tumor necrosis factor ligand superfamily member 11, soluble form: Secreted: O35235
Total number of polymer chains	3
Total formula weight	57169.08
Authors	Nelson, C.A.,Fremont, D.H. (deposition date: 2001-08-23, release date: 2001-09-12, Last modification date: 2023-08-16)
Primary citation	Lam, J.,Nelson, C.A.,Ross, F.P.,Teitelbaum, S.L.,Fremont, D.H. Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity J.Clin.Invest., 108:971-979, 2001 Cited by PubMed: 11581298 DOI: 10.1172/JCI200113890 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation