1JTV

Crystal structure of 17beta-Hydroxysteroid Dehydrogenase Type 1 complexed with Testosterone

Summary for 1JTV

Entry DOI	10.2210/pdb1jtv/pdb
Related	1IOL
Descriptor	17 beta-hydroxysteroid dehydrogenase type 1, TESTOSTERONE, GLYCEROL, ... (4 entities in total)
Functional Keywords	steroid hormones, alternative binding mode, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P14061
Total number of polymer chains	1
Total formula weight	35268.35
Authors	Shi, R.,Nahoum, V.,Lin, S.X. (deposition date: 2001-08-22, release date: 2003-06-24, Last modification date: 2023-08-16)
Primary citation	Gangloff, A.,Shi, R.,Nahoum, V.,Lin, S.X. Pseudo-symmetry of C19 steroids, alternative binding orientations, and multispecificity in human estrogenic 17beta-hydroxysteroid dehydrogenase. FASEB J., 17:274-276, 2003 Cited by PubMed: 12490543 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.54 Å)

Structure validation