1JQD

Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine

Summary for 1JQD

• Entry DOI: 10.2210/pdb1jqd/pdb
• Related: 1JQE
• Descriptor: Histamine N-Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, HISTAMINE, ... (4 entities in total)
• Functional Keywords: classic methyltransferase fold, protein-substrate-cofactor complex, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P50135
• Total number of polymer chains: 2
• Total formula weight: 67657.15

Authors

Horton, J.R.,Sawada, K.,Nishibori, M.,Zhang, X.,Cheng, X. (deposition date: 2001-08-06, release date: 2002-08-06, Last modification date: 2024-04-03)

• Primary citation: Horton, J.R.,Sawada, K.,Nishibori, M.,Zhang, X.,Cheng, X.; Two polymorphic forms of human histamine methyltransferase: structural, thermal, and kinetic comparisons.; Structure, 9:837-849, 2001; PubMed: 11566133; DOI: 10.1016/S0969-2126(01)00643-8

Experimental method

X-RAY DIFFRACTION (2.28 Å)