1JNH

Crystal Structure of Fab-Estradiol Complexes

Summary for 1JNH

Entry DOI	10.2210/pdb1jnh/pdb
Descriptor	monoclonal anti-estradiol 10G6D6 Fab light chain, monoclonal anti-estradiol 10G6D6 Fab heavy chain, ESTRADIOL-6 CARBOXYL-METHYL-OXIME, ... (4 entities in total)
Functional Keywords	igg fold, antibody-hapten complex, estradiol, immune system
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	8
Total formula weight	186559.71
Authors	Monnet, C.,Bettsworth, F.,Stura, E.A.,Le Du, M.-H.,Menez, R.,Derrien, L.,Zinn-Justin, S.,Gilquin, B.,Sibai, G.,Battail-Poirot, N.,Jolivet, M.,Menez, A.,Arnaud, M.,Ducancel, F.,Charbonnier, J.B. (deposition date: 2001-07-24, release date: 2002-02-06, Last modification date: 2023-08-16)
Primary citation	Monnet, C.,Bettsworth, F.,Stura, E.A.,Du, M.H.,Menez, R.,Derrien, L.,Zinn-Justin, S.,Gilquin, B.,Sibai, G.,Battail-Poirot, N.,Jolivet, M.,Menez, A.,Arnaud, M.,Ducancel, F.,Charbonnier, J.B. Highly specific anti-estradiol antibodies: structural characterisation and binding diversity. J.Mol.Biol., 315:699-712, 2002 Cited by PubMed: 11812141 DOI: 10.1006/jmbi.2001.5284 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.85 Å)

Structure validation