1JK8

Crystal structure of a human insulin peptide-HLA-DQ8 complex

Summary for 1JK8

• Entry DOI: 10.2210/pdb1jk8/pdb
• Descriptor: MHC class II HLA-DQ8, insulin B peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: hla-dq8, insulin b peptide, type 1 diabetes, autoimmunity, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 44768.13

Authors

Lee, K.H.,Wucherpfennig, K.W.,Wiley, D.C. (deposition date: 2001-07-11, release date: 2001-08-22, Last modification date: 2020-07-29)

• Primary citation: Lee, K.H.,Wucherpfennig, K.W.,Wiley, D.C.; Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.; Nat.Immunol., 2:501-507, 2001; PubMed: 11376336; DOI: 10.1038/88694

Experimental method

X-RAY DIFFRACTION (2.4 Å)