1JJB

A neutral molecule in cation-binding site: Specific binding of PEG-SH to Acetylcholinesterase from Torpedo californica

1JJB の概要

• エントリーDOI: 10.2210/pdb1jjb/pdb
• 関連するPDBエントリー: 1VXR 2ACE
• 分子名称: ACETYLCHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, ... (4 entities in total)
• 機能のキーワード: peg (polyethylene), serine hydrolase, alpha/beta hydrolase, neurotransmitter cleavage, catalytic triad, glycosylated protein, hydrolase
• 由来する生物種: Torpedo californica (Pacific electric ray)
• 細胞内の位置: Isoform H: Cell membrane; Lipid-anchor, GPI- anchor. Isoform T: Cell membrane; Peripheral membrane protein: P04058
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60978.84

構造登録者

Koellner, G.,Steiner, T.,Millard, C.B.,Silman, I.,Sussman, J.L. (登録日: 2001-07-04, 公開日: 2002-07-17, 最終更新日: 2021-06-02)

• 主引用文献: Koellner, G.,Steiner, T.,Millard, C.B.,Silman, I.,Sussman, J.L.; A neutral molecule in a cation-binding site: specific binding of a PEG-SH to acetylcholinesterase from Torpedo californica.; J.Mol.Biol., 320:721-725, 2002; PubMed: 12095250; DOI: 10.1016/S0022-2836(02)00475-8

実験手法

X-RAY DIFFRACTION (2.3 Å)