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1JIJ

Crystal structure of S. aureus TyrRS in complex with SB-239629

Summary for 1JIJ
Entry DOI10.2210/pdb1jij/pdb
Related1JII 1JIK 1JIL
Descriptortyrosyl-tRNA synthetase, [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID (2 entities in total)
Functional Keywordstyrosyl-trna synthetase, staphylococcus aureus, truncation, structure based inhibitor design, ligase
Biological sourceStaphylococcus aureus
Total number of polymer chains1
Total formula weight48070.84
Authors
Qiu, X.,Janson, C.A.,Smith, W.W.,Jarvest, R.L. (deposition date: 2001-07-02, release date: 2001-10-26, Last modification date: 2024-02-07)
Primary citationQiu, X.,Janson, C.A.,Smith, W.W.,Green, S.M.,McDevitt, P.,Johanson, K.,Carter, P.,Hibbs, M.,Lewis, C.,Chalker, A.,Fosberry, A.,Lalonde, J.,Berge, J.,Brown, P.,Houge-Frydrych, C.S.,Jarvest, R.L.
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors.
Protein Sci., 10:2008-2016, 2001
Cited by
PubMed: 11567092
DOI: 10.1110/ps.18001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.2 Å)
Structure validation

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