1JCZ

CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF HUMAN CARBONIC ANHYDRASE XII

Summary for 1JCZ

Entry DOI	10.2210/pdb1jcz/pdb
Descriptor	CARBONIC ANHYDRASE XII, ZINC ION, ACETIC ACID, ... (4 entities in total)
Functional Keywords	extracellular domain, human carbonic anhydrase xii, bitopic membrane protein, type i membrane protein, lyase
Biological source	Homo sapiens (human)
Cellular location	Membrane; Single-pass type I membrane protein: O43570
Total number of polymer chains	2
Total formula weight	59965.32
Authors	Whittington, D.A.,Waheed, A.,Ulmasov, B.,Shah, G.N.,Grubb, J.H.,Sly, W.S.,Christianson, D.W. (deposition date: 2001-06-11, release date: 2001-08-17, Last modification date: 2023-08-16)
Primary citation	Whittington, D.A.,Waheed, A.,Ulmasov, B.,Shah, G.N.,Grubb, J.H.,Sly, W.S.,Christianson, D.W. Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells. Proc.Natl.Acad.Sci.USA, 98:9545-9550, 2001 Cited by PubMed: 11493685 DOI: 10.1073/pnas.161301298 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation