1J96

Human 3alpha-HSD type 3 in Ternary Complex with NADP and Testosterone

Summary for 1J96

• Entry DOI: 10.2210/pdb1j96/pdb
• Descriptor: 3alpha-hydroxysteroid dehydrogenase type 3, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: aldo-keto reductase, steroid metabolism, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (Potential): P52895
• Total number of polymer chains: 2
• Total formula weight: 75722.07

Authors

Nahoum, V.,Labrie, F.,Lin, S.-X. (deposition date: 2001-05-23, release date: 2002-05-23, Last modification date: 2023-08-16)

• Primary citation: Nahoum, V.,Gangloff, A.,Legrand, P.,Zhu, D.W.,Cantin, L.,Zhorov, B.S.,Luu-The, V.,Labrie, F.,Breton, R.,Lin, S.X.; Structure of the human 3alpha-hydroxysteroid dehydrogenase type 3 in complex with testosterone and NADP at 1.25-A resolution.; J.Biol.Chem., 276:42091-42098, 2001; PubMed: 11514561; DOI: 10.1074/jbc.M105610200

Experimental method

X-RAY DIFFRACTION (1.25 Å)