1J8E

Crystal structure of ligand-binding repeat CR7 from LRP

Summary for 1J8E

• Entry DOI: 10.2210/pdb1j8e/pdb
• Related: 1AJJ 1CR8 1D2L
• Descriptor: LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1, CALCIUM ION (3 entities in total)
• Functional Keywords: ligand binding, calcium binding, complement-like repeat, lrp receptor, signaling protein
• Biological source: Homo sapiens (human)
• Cellular location: Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm: Q07954
• Total number of polymer chains: 1
• Total formula weight: 4857.10

Authors

Simonovic, M.,Dolmer, K.,Huang, W.,Strickland, D.K.,Volz, K.,Gettins, P.G.W. (deposition date: 2001-05-21, release date: 2001-12-19, Last modification date: 2021-10-27)

• Primary citation: Simonovic, M.,Dolmer, K.,Huang, W.,Strickland, D.K.,Volz, K.,Gettins, P.G.; Calcium coordination and pH dependence of the calcium affinity of ligand-binding repeat CR7 from the LRP. Comparison with related domains from the LRP and the LDL receptor.; Biochemistry, 40:15127-15134, 2001; PubMed: 11735395; DOI: 10.1021/bi015688m

Experimental method

X-RAY DIFFRACTION (1.85 Å)