1IYJ

STRUCTURE OF A BRCA2-DSS1 COMPLEX

Summary for 1IYJ

• Entry DOI: 10.2210/pdb1iyj/pdb
• Related: 1MIU 1MJE
• Descriptor: Deleted in split hand/split foot protein 1, breast cancer susceptibility (2 entities in total)
• Functional Keywords: tumor suppressor, breast cancer susceptibility, dna-binding, gene regulation-antitumor protein complex, gene regulation/antitumor protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 200018.88

Authors

Pavletich, N.P.,Jeffrey, P.D.,Yang, H.J. (deposition date: 2002-08-28, release date: 2002-10-02, Last modification date: 2023-12-27)

• Primary citation: Yang, H.,Jeffrey, P.D.,Miller, J.,Kinnucan, E.,Sun, Y.,Thoma, N.H.,Zheng, N.,Chen, P.L.,Lee, W.H.,Pavletich, N.P.; BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.; Science, 297:1837-1848, 2002; PubMed: 12228710; DOI: 10.1126/science.297.5588.1837

Experimental method

X-RAY DIFFRACTION (3.4 Å)