1IHS

CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6

1IHS の概要

• エントリーDOI: 10.2210/pdb1ihs/pdb
• 分子名称: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUTONIN, ... (4 entities in total)
• 機能のキーワード: hydrolase(serine proteinase), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P28504
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36410.39

構造登録者

Zdanov, A.,Cygler, M. (登録日: 1993-08-04, 公開日: 1994-01-31, 最終更新日: 2023-11-15)

• 主引用文献: Zdanov, A.,Wu, S.,DiMaio, J.,Konishi, Y.,Li, Y.,Wu, X.,Edwards, B.F.,Martin, P.D.,Cygler, M.; Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6.; Proteins, 17:252-265, 1993; PubMed: 8272424; DOI: 10.1002/prot.340170304

実験手法

X-RAY DIFFRACTION (2 Å)