1IHS

CRYSTAL STRUCTURE OF THE COMPLEX OF HUMAN ALPHA-THROMBIN AND NON-HYDROLYZABLE BIFUNCTIONAL INHIBITORS, HIRUTONIN-2 AND HIRUTONIN-6

Summary for 1IHS

Entry DOI	10.2210/pdb1ihs/pdb
Descriptor	ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUTONIN, ... (4 entities in total)
Functional Keywords	hydrolase(serine proteinase), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734 Secreted: P28504
Total number of polymer chains	3
Total formula weight	36410.39
Authors	Zdanov, A.,Cygler, M. (deposition date: 1993-08-04, release date: 1994-01-31, Last modification date: 2023-11-15)
Primary citation	Zdanov, A.,Wu, S.,DiMaio, J.,Konishi, Y.,Li, Y.,Wu, X.,Edwards, B.F.,Martin, P.D.,Cygler, M. Crystal structure of the complex of human alpha-thrombin and nonhydrolyzable bifunctional inhibitors, hirutonin-2 and hirutonin-6. Proteins, 17:252-265, 1993 Cited by PubMed: 8272424 DOI: 10.1002/prot.340170304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation