1IAN

HUMAN P38 MAP KINASE INHIBITOR COMPLEX

Summary for 1IAN

Entry DOI	10.2210/pdb1ian/pdb
Descriptor	P38 MAP KINASE, 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE (2 entities in total)
Functional Keywords	protein ser/thr-kinase, serine/threonine-protein kinase, serine-threonine-protein kinase complex
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q16539
Total number of polymer chains	1
Total formula weight	43561.03
Authors	Tong, L. (deposition date: 1997-03-07, release date: 1998-05-06, Last modification date: 2024-04-03)
Primary citation	Tong, L.,Pav, S.,White, D.M.,Rogers, S.,Crane, K.M.,Cywin, C.L.,Brown, M.L.,Pargellis, C.A. A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket. Nat.Struct.Biol., 4:311-316, 1997 Cited by PubMed: 9095200 DOI: 10.1038/nsb0497-311 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation