1I90

CARBONIC ANHYDRASE II COMPLEXED WITH AL-8520 2H-THIENO[3,2-E]-1,2-THIAZINE-6-SULFONAMIDE, 4-AMINO-3,4-DIHYDRO-2-(3-METHOXYPROPYL)-, 1,1-DIOXIDE, (R)

Summary for 1I90

Entry DOI	10.2210/pdb1i90/pdb
Related	1I8z 1I91
Descriptor	CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total)
Functional Keywords	carbonic anhydrase ii, al-8520, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29777.30
Authors	Kim, C.-Y.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W. (deposition date: 2001-03-16, release date: 2001-03-28, Last modification date: 2024-02-07)
Primary citation	Kim, C.Y.,Whittington, D.A.,Chang, J.S.,Liao, J.,May, J.A.,Christianson, D.W. Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV. J.Med.Chem., 45:888-893, 2002 Cited by PubMed: 11831900 DOI: 10.1021/jm010163d PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation