1I8K

CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE

1I8K の概要

• エントリーDOI: 10.2210/pdb1i8k/pdb
• 関連するPDBエントリー: 1I8I
• 分子名称: EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII PEPTIDE ANTIGEN, ... (4 entities in total)
• 機能のキーワード: antibody-peptide complex, immunoglobulin fold, peptide antigen, type ii' beta turn., immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 26878.92

構造登録者

Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V. (登録日: 2001-03-14, 公開日: 2002-03-14, 最終更新日: 2021-10-27)

• 主引用文献: Landry, R.C.,Klimowicz, A.C.,Lavictoire, S.J.,Borisova, S.,Kottachchi, D.T.,Lorimer, I.A.,Evans, S.V.; Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII.; J.Mol.Biol., 308:883-893, 2001; PubMed: 11352579; DOI: 10.1006/jmbi.2001.4628

実験手法

X-RAY DIFFRACTION (1.8 Å)