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1I44

CRYSTALLOGRAPHIC STUDIES OF AN ACTIVATION LOOP MUTANT OF THE INSULIN RECEPTOR TYROSINE KINASE

Summary for 1I44
Entry DOI10.2210/pdb1i44/pdb
Related1IR3 1IRK
DescriptorINSULIN RECEPTOR, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (4 entities in total)
Functional Keywordsprotein tyrosine kinase, phosphotransferase, transferase
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein: P06213
Total number of polymer chains1
Total formula weight35278.31
Authors
Till, J.H.,Ablooglu, A.J.,Frankel, M.,Kohanski, R.A.,Hubbard, S.R. (deposition date: 2001-02-19, release date: 2001-03-07, Last modification date: 2023-08-09)
Primary citationTill, J.H.,Ablooglu, A.J.,Frankel, M.,Bishop, S.M.,Kohanski, R.A.,Hubbard, S.R.
Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.
J.Biol.Chem., 276:10049-10055, 2001
Cited by
PubMed: 11124964
DOI: 10.1074/jbc.M010161200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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