1HVU

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT

Summary for 1HVU

Entry DOI	10.2210/pdb1hvu/pdb
Descriptor	RNA (33 NUCLEOTIDE RNA PSEUDOKNOT), PROTEIN (HIV-1 REVERSE TRANSCRIPTASE) (3 entities in total)
Functional Keywords	complex (nucleotidyltransferase-rna), hydrolase, aspartyl protease, endonuclease, transferase-rna complex, transferase/rna
Biological source	Human immunodeficiency virus 1 More
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366
Total number of polymer chains	12
Total formula weight	492023.45
Authors	Jaeger, J.,Restle, T.,Steitz, T.A. (deposition date: 1998-06-30, release date: 1999-01-13, Last modification date: 2023-08-02)
Primary citation	Jaeger, J.,Restle, T.,Steitz, T.A. The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. EMBO J., 17:4535-4542, 1998 Cited by PubMed: 9687519 DOI: 10.1093/emboj/17.15.4535 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4.75 Å)

Structure validation