1HUQ

1.8A CRYSTAL STRUCTURE OF THE MONOMERIC GTPASE RAB5C (MOUSE)

Summary for 1HUQ

Entry DOI	10.2210/pdb1huq/pdb
Related	1D5C 1EK0 1G16 1ZBD 3RAB 5P21
Descriptor	RAB5C, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
Functional Keywords	g-protein, gtp hydrolysis, endocytosis, rab protein, membrane trafficking, protein transport
Biological source	Mus musculus (house mouse)
Cellular location	Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P35278
Total number of polymer chains	1
Total formula weight	18820.33
Authors	Merithew, E.,Hatherly, S.,Dumas, J.J.,Lawe, D.C.,Heller-Harrison, R.,Lambright, D.G. (deposition date: 2001-01-04, release date: 2001-02-07, Last modification date: 2023-08-09)
Primary citation	Merithew, E.,Hatherly, S.,Dumas, J.J.,Lawe, D.C.,Heller-Harrison, R.,Lambright, D.G. Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition. J.Biol.Chem., 276:13982-13988, 2001 Cited by PubMed: 11278565 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation