1HRE

SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4

Summary for 1HRE

Entry DOI	10.2210/pdb1hre/pdb
Descriptor	HEREGULIN ALPHA (1 entity in total)
Functional Keywords	growth factor
Biological source	Homo sapiens (human)
Cellular location	Pro-neuregulin-1, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Neuregulin-1: Secreted. Isoform 8: Nucleus. Isoform 9: Secreted. Isoform 10: Membrane; Single-pass type I membrane protein: Q02297
Total number of polymer chains	1
Total formula weight	7544.69
Authors	Nagata, K.,Kohda, D.,Hatanaka, H.,Ichikawa, S.,Inagaki, F. (deposition date: 1994-07-21, release date: 1994-10-15, Last modification date: 2017-11-29)
Primary citation	Nagata, K.,Kohda, D.,Hatanaka, H.,Ichikawa, S.,Matsuda, S.,Yamamoto, T.,Suzuki, A.,Inagaki, F. Solution structure of the epidermal growth factor-like domain of heregulin-alpha, a ligand for p180erbB-4. EMBO J., 13:3517-3523, 1994 Cited by PubMed: 8062828 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation