1HQU

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

Summary for 1HQU

• Entry DOI: 10.2210/pdb1hqu/pdb
• Related: 1HPZ 1HQE
• Descriptor: POL POLYPROTEIN, (S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE (3 entities in total)
• Functional Keywords: nucleotidyltransferase, transferase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366
• Total number of polymer chains: 2
• Total formula weight: 115093.03

Authors

Hsiou, Y.,Ding, J.,Arnold, E. (deposition date: 2000-12-19, release date: 2001-05-30, Last modification date: 2023-08-09)

• Primary citation: Hsiou, Y.,Ding, J.,Das, K.,Clark Jr., A.D.,Boyer, P.L.,Lewi, P.,Janssen, P.A.,Kleim, J.P.,Rosner, M.,Hughes, S.H.,Arnold, E.; The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.; J.Mol.Biol., 309:437-445, 2001; PubMed: 11371163; DOI: 10.1006/jmbi.2001.4648

Experimental method

X-RAY DIFFRACTION (2.7 Å)