1HNN

CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)

Summary for 1HNN

Entry DOI	10.2210/pdb1hnn/pdb
Descriptor	PHENYLETHANOLAMINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE, ... (4 entities in total)
Functional Keywords	methyltransferase, adrenaline synthesis, s-adenosyl methionine, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	62969.32
Authors	Martin, J.L.,Begun, J.,McLeish, M.J.,Caine, J.M.,Grunewald, G.L. (deposition date: 2000-12-07, release date: 2001-12-07, Last modification date: 2024-02-07)
Primary citation	Martin, J.L.,Begun, J.,McLeish, M.J.,Caine, J.M.,Grunewald, G.L. Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT. Structure, 9:977-985, 2001 Cited by PubMed: 11591352 DOI: 10.1016/S0969-2126(01)00662-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation