1HE1
Crystal structure of the complex between the GAP domain of the Pseudomonas aeruginosa ExoS toxin and human Rac
Summary for 1HE1
Entry DOI | 10.2210/pdb1he1/pdb |
Related | 1E96 1HE9 1MH1 |
NMR Information | BMRB: 5511 |
Descriptor | EXOENZYME S, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, NICKEL (II) ION, ... (7 entities in total) |
Functional Keywords | signaling protein, signalling complex, exos, rac, pseudomonas aeruginosa, gap, toxin, virulence factor, transition state, protein-protein complex, gtpase, signal transduction |
Biological source | PSEUDOMONAS AERUGINOSA More |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P15154 |
Total number of polymer chains | 4 |
Total formula weight | 68987.09 |
Authors | Wurtele, M.,Wolf, E.,Pederson, K.J.,Buchwald, G.,Ahmadian, M.R.,Barbieri, J.T.,Wittinghofer, A. (deposition date: 2000-11-18, release date: 2001-01-02, Last modification date: 2023-12-13) |
Primary citation | Wurtele, M.,Wolf, E.,Pederson, K.J.,Buchwald, G.,Ahmadian, M.R.,Barbieri, J.T.,Wittinghofer, A. How the Pseudomonas Aeruginosa Exos Toxin Downregulates Rac Nat.Struct.Biol., 8:23-, 2001 Cited by PubMed: 11135665DOI: 10.1038/83007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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