1HAV

HEPATITIS A VIRUS 3C PROTEINASE

Summary for 1HAV

• Entry DOI: 10.2210/pdb1hav/pdb
• Descriptor: HEPATITIS A VIRUS 3C PROTEINASE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: polyprotein, coat protein, core protein, rna-directed rna polymerase, hydrolase, thiol protease
• Biological source: Hepatitis A virus; More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein VP1-2A: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3ABC: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3AB: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P08617 P08617
• Total number of polymer chains: 2
• Total formula weight: 47892.58

Authors

Bergmann, E.M.,James, M.N.G. (deposition date: 1996-10-23, release date: 1996-12-23, Last modification date: 2024-04-03)

• Primary citation: Bergmann, E.M.,Mosimann, S.C.,Chernaia, M.M.,Malcolm, B.A.,James, M.N.; The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition.; J.Virol., 71:2436-2448, 1997; PubMed: 9032381

Experimental method

X-RAY DIFFRACTION (2 Å)