1HAF

HEREGULIN-ALPHA EPIDERMAL GROWTH FACTOR-LIKE DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE

Summary for 1HAF

• Entry DOI: 10.2210/pdb1haf/pdb
• Descriptor: HEREGULIN-ALPHA (1 entity in total)
• Functional Keywords: growth factor
• Biological source: Homo sapiens (human)
• Cellular location: Pro-neuregulin-1, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Neuregulin-1: Secreted. Isoform 8: Nucleus. Isoform 9: Secreted. Isoform 10: Membrane; Single-pass type I membrane protein: Q02297
• Total number of polymer chains: 1
• Total formula weight: 7129.22

Authors

Jacobsen, N.E.,Skelton, N.J.,Fairbrother, W.J. (deposition date: 1995-11-30, release date: 1996-07-11, Last modification date: 2022-02-23)

• Primary citation: Jacobsen, N.E.,Abadi, N.,Sliwkowski, M.X.,Reilly, D.,Skelton, N.J.,Fairbrother, W.J.; High-resolution solution structure of the EGF-like domain of heregulin-alpha.; Biochemistry, 35:3402-3417, 1996; PubMed: 8639490; DOI: 10.1021/bi952626l

Experimental method

SOLUTION NMR